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May 8, 2007

Cinnamon and Polycystic Ovary Syndrome

May 08th 2007 Posted to PCOS

Information on a study in to the effect of cinnamon extract on insulin resistance parameters in polycystic ovary syndrome

A pilot study (Phase I - first study on a small number of patients to basically prove a theory and use as a basis of a larger study - Phase II)

Wang JG, Anderson RA, Graham GM 3rd, Chu MC, Sauer MV, Guarnaccia MM, Lobo RA.
Department of Obstetrics & Gynecology, Division of Reproductive Endocrinology, College of Physicians & Surgeons, Columbia University, New York, New York.
Cinnamon extract has been shown to reduce insulin resistance in in vitro and in vivo studies by increasing phosphatidylinositol 3-kinase activity in the insulin signaling pathway and thus potentiating insulin action.

Fifteen women with polycystic ovary syndrome (PCOS) were randomized to daily oral cinnamon and placebo for 8 weeks. Comparisons of post-treatment to baseline insulin sensitivity indices using fasting and 2-hour oral glucose tolerance tests showed significant reductions in insulin resistance in the cinnamon group but not in the placebo group.

A larger trial is needed to confirm the findings of this pilot study and to evaluate the effect of cinnamon extract on menstrual cyclicity.


April 17, 2007

Cinnamon and Diabetes Disease Type Appears to Matter

April 17th 2007 Posted to Diabetes

Science News article by Janet Raloff

Cinnamon—it’s not just for perking up the flavor of pies and applesauce anymore. A teaspoonful of the spice can have medicinal properties, at least for most people with diabetes, several trials have indicated. However, the latest study identifies one population that cinnamon doesn’t seem to benefit: individuals suffering from what was once referred to as juvenile diabetes.

(Read the article)


April 8, 2007

Cinnamon does not aid Type 1 Diabetes control

April 08th 2007 Posted to Diabetes

NEW YORK (Reuters Health) - Despite earlier promising findings, it seems unlikely that cinnamon can improve blood sugar levels in people with type 1, or insulin-dependent, diabetes, researchers report.

Previous research has shown that cinnamon appears to help fat cells recognize and respond to insulin. In test tube experiments and in animal studies, the spice led to a noteworthy increase in the processing of glucose. (Read the article)


April 2, 2007

New cinnamon clinical trial in Florida

April 02nd 2007 Posted to Diabetes

A new clinical study into the use of cinnamon in the care of type 2 diabetes (Non-Insulin Dependent Diabetes Mellitus - NIDDM) has just started at the Eglin AFB Regional Hospital in Florida, USA.

The trial is designed to run from March 2007 to August 2007 for 140 patients with type 2 diabetes between 18 - 90 years of age. (Read the article)